ARYx aggressively pursues patents and other forms of protection for our technologies, inventions, and improvements. Our pipeline of drug candidates is protected by global filings of patents, both issued and pending, that broadly cover the composition of matter. All drug candidates are classified as new chemical entities (NCEs) and have the same patent protection as any novel pharmaceutical.
| ARYx Therapeutics Patents (As of 3.31.10) | |
| Issued or Allowed U.S. Patents | 44 |
| Pending U.S. Patent Applications | 15 |
| Issued Foreign Patents | 114 |
| Pending Foreign Patent Applications | 102 |
| TOTAL: | 275 |



